Wang Fulin, Qiao Guangyu, Li Xianghong, Gui Qiuping
Department of Pathology, People's Liberation Army General Hospital, Beijing, China.
Neurosurgery. 2007 Aug;61(2):E420; discussion E420. doi: 10.1227/01.NEU.0000255530.46092.AA.
Dysembryoplastic neuroepithelial tumors (DNTs) are clinicopathologically unique tumors. They are usually located within the supratentorial cortex, most often in the temporal lobe. These lesions are frequently associated with intractable complex partial seizures in children and young adults. DNTs may also arise outside of the cerebral cortex. We report a case of a 57-year-old woman who had a DNT in the caudate nucleus. During a 7-year follow-up period, the tumor did not recur. The literature on DNTs with atypical "ectopic" localizations is summarized.
A patient presented with a 1-year history of headaches, nausea and vomiting, and progressive visual disturbances.
Gross subtotal removal of the lesion was accomplished without further treatment.
Unlike diffuse gliomas, such as oligodendrogliomas and central neurocytomas, DNTs are benign lesions with a favorable prognosis after surgical resection. Therefore, recognition of DNTs at atypical ectopic locations is essential for predicting the clinical course and for making the right therapeutic decisions.
胚胎发育不良性神经上皮肿瘤（DNTs）是临床病理特征独特的肿瘤。它们通常位于幕上皮质内，最常见于颞叶。这些病变常与儿童和青年的顽固性复杂部分性癫痫发作相关。DNTs也可能起源于大脑皮质以外。我们报告一例57岁女性，其尾状核存在DNT。在7年的随访期内，肿瘤未复发。本文总结了关于具有非典型“异位”定位的DNTs的文献。
一名患者有1年的头痛、恶心、呕吐及进行性视力障碍病史。
在未进行进一步治疗的情况下实现了病变的大体次全切除。
与弥漫性胶质瘤，如少突胶质细胞瘤和中枢神经细胞瘤不同，DNTs是良性病变，手术切除后预后良好。因此识别非典型异位部位的DNTs对于预测临床病程和做出正确的治疗决策至关重要。
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