Terauchi Masakazu, Kubota Toshiro, Aso Takeshi, Maehara Taketoshi
Department of Comprehensive Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Bunkyo, Tokyo, Japan.
Obstet Gynecol. 2006 Sep;108(3 Pt 2):730-2. doi: 10.1097/01.AOG.0000188061.14425.e2.
Dysembryoplastic neuroepithelial tumor is a rare, low-grade brain tumor that is characterized by intractable, partial seizures of juvenile onset.
A 36-year-old pregnant woman with dichorionic, diamniotic twins temporarily lost consciousness at 27 weeks of gestation. Magnetic resonance imaging evaluation showed a 3-cm multicystic nodule in her right temporal lobe that was diagnosed, together with her history of recurrent anxiety attacks, as dysembryoplastic neuroepithelial tumor. The lesion did not enlarge during pregnancy, and healthy male infants were delivered by cesarean at 36 weeks. The tumor was successfully removed 2 months postpartum, and the patient has experienced no further seizures.
Dysembryoplastic neuroepithelial tumor was conservatively managed during pregnancy without neurosurgical intervention.
胚胎发育不良性神经上皮肿瘤是一种罕见的低级别脑肿瘤，其特征为青少年期起病的难治性部分性癫痫发作。
一名怀有双绒毛膜、双羊膜囊双胞胎的36岁孕妇在妊娠27周时短暂失去意识。磁共振成像评估显示其右侧颞叶有一个3厘米的多囊性结节，结合其反复焦虑发作史，诊断为胚胎发育不良性神经上皮肿瘤。孕期病变未增大，36周时剖宫产娩出健康男婴。产后2个月成功切除肿瘤，患者未再出现癫痫发作。
胚胎发育不良性神经上皮肿瘤在孕期采取保守治疗，未进行神经外科干预。
