高流量鼻导管作为一种在婴儿中提供持续气道正压的设备。
High-flow nasal cannula as a device to provide continuous positive airway pressure in infants.
作者信息
Spence K L, Murphy D, Kilian C, McGonigle R, Kilani R A
机构信息
Division of Newborn Medicine, the Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St Louis Children's Hospital, St Louis, MO, USA.
出版信息
J Perinatol. 2007 Dec;27(12):772-5. doi: 10.1038/sj.jp.7211828. Epub 2007 Aug 30.
OBJECTIVE
To measure the intrapharyngeal pressure (IPP) generated by high-flow nasal cannula (HFNC) at varying flow rates up to 5 l min(-1).
STUDY DESIGN
We studied 14 infants on HFNC or NCPAP using IPP manometry to measure the IPP generated at flows of 1, 2, 3, 4 and 5 l min(-1).
RESULT
On average flow rates of 1, 2, 3, 4 and 5 l min(-1) generated an IPP (cm of H(2)O) of 1.70+/-0.34, 1.75+/-0.2, 2.62+/-0.28, 3.78+/-0.44 and 4.84+/-0.51 respectively.
CONCLUSION
HFNC delivers significant IPP and is potentially a well-tolerated and viable option to provide CPAP at flows of > or = 3 min(-1) in infants with respiratory distress.
目的
测量高流量鼻导管（HFNC）在高达5升/分钟的不同流速下产生的咽内压（IPP）。
研究设计
我们使用IPP测压法研究了14名使用HFNC或NCPAP的婴儿，以测量在1、2、3、4和5升/分钟流速下产生的IPP。
结果
平均而言，1、2、3、4和5升/分钟的流速分别产生的IPP（厘米水柱）为1.70±0.34、1.75±0.2、2.62±0.28、3.78±0.44和4.84±0.51。
结论
HFNC可产生显著的IPP，对于呼吸窘迫的婴儿，在流速≥3升/分钟时，它可能是一种耐受性良好且可行的提供持续气道正压通气（CPAP）的选择。
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