Iaccheri Barbara, Fiore Tito, Cagini Carlo, Giansanti Fabrizio, Androudi Sofia, Brazitikos Periklis D
Department of Ophthalmology, Monteluce Hospital, University of Perugia, Perugia, Italy.
Semin Ophthalmol. 2007 Jul-Sep;22(3):171-3. doi: 10.1080/08820530701501006.
The purpose of this article is to report a case of retinal astrocytic hamartoma with an associated macular edema and the spontaneous resolution of the latter due to an increase in hamartoma calcification over a seven-year follow-up period. Clinical examination, red-free and colour fundus photographs, fluorescein angiography, and optical coherence tomography were performed during a seven-year follow-up. We conclude that retinal astrocytic hamartomas may be associated with cystoid macular edema. In some cases, the CME may resolve due to an increase in tumor calcification. Whether the progressive calcification of the retinal mass represents an overall positive prognostic factor is still unknown and further histologic studies are certainly required.
本文旨在报告一例伴有黄斑水肿的视网膜星形细胞瘤病例,以及在七年随访期间,由于肿瘤钙化增加,黄斑水肿自发消退。在七年随访期间进行了临床检查、无赤光眼底照相、荧光素血管造影和光学相干断层扫描。我们得出结论,视网膜星形细胞瘤可能与黄斑囊样水肿有关。在某些情况下,黄斑囊样水肿可能因肿瘤钙化增加而消退。视网膜肿物的渐进性钙化是否代表总体良好的预后因素仍不清楚,当然还需要进一步的组织学研究。