使用脉搏传输时间作为阻塞性睡眠呼吸暂停患者自主神经唤醒的一种测量方法。

Use of pulse transit time as a measure of autonomic arousals in patients with obstructive sleep apnea.

作者信息

Xiao Yi, Zhong Xu, Huang Rong

机构信息

Department of Pulmonary Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730.

出版信息

Chin Med Sci J. 2007 Jun;22(2):89-92.

PMID:17763579

Abstract

OBJECTIVE

To evaluate the feasibility of pulse transit time (PTT) arousals as an index of sleep fragmentation in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).

METHODS

Individuals referred for evaluation of possible OSAHS underwent overnight polysomnography (PSG). Three conventional indices of sleep fragmentation [electroencephalography (EEG) arousals, apnea/hypopnea index (AHI) , oxygen desaturation index (ODI)] , PTT arousals, and Epworth sleepiness scale (ESS) were compared.

RESULTS

PTT arousals were positively correlated with EEG arousals (r = 0.746, P < 0.001), AHI (r = 0.786, P < 0.001), and ODI (r = 0.665, P < 0.001) , respectively. But, both PTT arousals and EEG arousals had no correlation with ESS (r = 0.432, P = 0.201; r = 0.196, P = 0.591, respectively).

CONCLUSION

PTT arousals are correlated well with other standard measures estimating severity of OSAHS and potentially a non-invasive marker with which to measure the sleep fragmentation in patients with OSAHS.

摘要

目的

评估脉搏传导时间（PTT）觉醒作为阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者睡眠片段化指标的可行性。

方法

对因可能患有OSAHS而前来评估的个体进行整夜多导睡眠图（PSG）检查。比较了三种传统的睡眠片段化指标[脑电图（EEG）觉醒、呼吸暂停/低通气指数（AHI）、氧饱和度下降指数（ODI）]、PTT觉醒和爱泼沃斯思睡量表（ESS）。

结果

PTT觉醒分别与EEG觉醒（r = 0.746，P < 0.001）、AHI（r = 0.786，P < 0.001）和ODI（r = 0.665，P < 0.001）呈正相关。但是，PTT觉醒和EEG觉醒均与ESS无相关性（分别为r = 0.432，P = 0.201；r = 0.196，P = 0.591）。