Petersen K R, Brooks L, Jacobsen B, Skouby S O
Department of Obstetrics and Gynecology, Herlev University Hospital, Denmark.
Adv Contracept. 1991 Dec;7(4):333-8. doi: 10.1007/BF02340179.
The majority of studies on the clinical events following the insertion of an intrauterine device for contraception have observed a higher frequency of adverse effects in nulliparous women. In this review, the significance of nulliparity on the occurrence of medical removal for bleeding and pain, expulsion and pelvic inflammatory disease is estimated. The possible role of the anatomy of the pregravid uterus is discussed, and results obtained through a selective measurement of the endometrial cavity in a population of nulligravidas is presented. It is concluded that IUDs should not be the first choice of contraception in nulliparous women because of an increased risk of long-term adverse effects. The relationship between the length of the intrauterine device and the length of the endometrial cavity does not seem to be of clinical significance for the performance of IUDs in nulliparous women.
大多数关于宫内节育器避孕后临床事件的研究发现，未生育女性出现不良反应的频率更高。在本综述中，评估了未生育状态对因出血和疼痛进行医学取出、节育器脱落及盆腔炎发生的影响。讨论了未孕子宫解剖结构可能发挥的作用，并展示了在未孕人群中对子宫内膜腔进行选择性测量所获得的结果。得出的结论是，由于长期不良反应风险增加，宫内节育器不应作为未生育女性避孕的首选。宫内节育器的长度与子宫内膜腔的长度之间的关系，对于未生育女性使用宫内节育器的效果似乎并无临床意义。
