Kim Yong Min, Kim Ah Young, Park Yong Ho, Kim Dong Hyun, Rha Ki-Sang
Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejon, Korea.
Otolaryngol Head Neck Surg. 2007 Sep;137(3):500-4. doi: 10.1016/j.otohns.2007.04.009.
To elucidate the clinical characteristics of nasal tuberculosis and to discuss its diagnostic difficulties.
Retrospective clinical analysis.
A total of eight patients presented with nasal tuberculosis during the study period (from January 1989 through December 2006). Six were female and two were male. The patient age varied from 17 to 51 years, with a mean of 31 years. The most commonly involved site was the nasal septum (7 of 8). Perforation of the nasal septum was observed in three cases. Sinus invasion was observed in two cases and required sinus surgery. Six of the cases were a result of primary infections, while two were secondary disease manifestations. All patients were treated with anti-tuberculosis medications, with subsequent improvement with regard to clinical symptoms and physical signs.
We present the largest number of nasal tuberculosis cases reported in the medical literature from a single institute. Diagnosing nasal tuberculosis requires a high index of suspicion and occasionally the use of experimental drug treatment options.
阐明鼻结核的临床特征并探讨其诊断难点。
回顾性临床分析。
在研究期间（1989年1月至2006年12月）共有8例鼻结核患者。其中6例为女性，2例为男性。患者年龄在17至51岁之间，平均年龄为31岁。最常受累的部位是鼻中隔（8例中的7例）。3例观察到鼻中隔穿孔。2例观察到鼻窦受累，需要进行鼻窦手术。6例为原发性感染，2例为继发性疾病表现。所有患者均接受抗结核药物治疗，随后临床症状和体征有所改善。
我们展示了单一机构在医学文献中报道的数量最多的鼻结核病例。诊断鼻结核需要高度的怀疑指数，有时还需要采用试验性药物治疗方案。
