Thomson F J, Masson E A, Leeming J T, Boulton A J
Manchester Royal Infirmary.
Age Ageing. 1991 Nov;20(6):404-6. doi: 10.1093/ageing/20.6.404.
The knowledge of symptoms of hypoglycaemia of 45 consecutive elderly diabetic patients was assessed during a structured interview and compared with that of an age-matched non-diabetic control group. Twenty-three (88%) patients taking oral hypoglycaemic agents (OHAs) and six (32%) insulin-treated patients denied any knowledge of hypoglycaemia. There was no significant difference in knowledge of 14 symptoms of hypoglycaemia between the non-diabetic controls and the combined diabetic (OHA and insulin) groups, but insulin-treated patients were slightly more knowledgeable than patients taking OHAs. Fourteen (54%) of the OHA group were taking either glibenclamide or chlorpropamide which have been associated with severe and prolonged hypoglycaemia. Elderly diabetic patients are unlikely to respond to the warning symptoms of hypoglycaemia and caution should therefore be exercised when prescribing for these patients.
在一次结构化访谈中评估了45例连续的老年糖尿病患者对低血糖症状的了解情况，并与年龄匹配的非糖尿病对照组进行了比较。23例（88%）口服降糖药（OHA）的患者和6例（32%）接受胰岛素治疗的患者否认对低血糖有任何了解。非糖尿病对照组与联合糖尿病（OHA和胰岛素）组在14种低血糖症状的知晓方面没有显著差异，但接受胰岛素治疗的患者比服用OHA的患者略了解更多。OHA组中有14例（54%）正在服用与严重和持续性低血糖有关的格列本脲或氯磺丙脲。老年糖尿病患者不太可能对低血糖的警示症状做出反应，因此在为这些患者开处方时应谨慎。
