Clerihew L, McGuire W
Ninewells Hospital and Medical School, Dundee, Scotland.
Arch Dis Child Fetal Neonatal Ed. 2008 May;93(3):F238-9. doi: 10.1136/adc.2007.121830. Epub 2007 Sep 3.
In a UK-wide survey, 28% of neonatal units reported using systemic or topical/oral antifungal prophylaxis for very low birthweight infants. Systemic prophylaxis is targeted to extremely preterm infants with additional risk factors for invasive fungal infection. Currently, there seems to be sufficient variation in practice to undertake randomised trials of these interventions.
在一项全英国范围的调查中,28%的新生儿病房报告称对极低出生体重儿使用全身性或局部/口服抗真菌预防措施。全身性预防措施针对的是有侵袭性真菌感染额外风险因素的极早产儿。目前,在实践中似乎存在足够的差异来开展这些干预措施的随机试验。