Science. 1970 May 15;168(3933):849-50. doi: 10.1126/science.168.3933.849.
Large doses of L-dopa given to mice produced marked increases in brain dopamine, no change in norepinephrine, and a remarkable decrease in brain serotonin. This reduction apparently results from a release or displacement, or both, of serotonin from its storage sites.
给老鼠大剂量的 L-多巴会显著增加大脑中的多巴胺,而不会改变去甲肾上腺素,却会显著减少大脑中的血清素。这种减少显然是由于血清素从其储存部位释放或取代,或者两者兼而有之。