[单克隆抗体D12所揭示的杯状细胞抗原]
[Goblet cell antigen revealed by monoclonal antibody D12].
作者信息
Pugachev K K, Egorova S G, Shimbireva I B
出版信息
Biull Eksp Biol Med. 1991 Dec;112(12):629-31.
PMID:1777634
Abstract
An antigen from meconium was revealed by monoclonal antibody D 12 (IgM). This antigen was heat liable substance with relative m. m. about 400-600 kD. Reactions on histological slides with MAb D 12 were blocked up after processing tissues by neuraminidase and become stronger after processing tissues by NaIO4. Antigen D 12 was found in goblet cells of fetal and definitive colon and in analogous cells of trachea and bronchi.
摘要
单克隆抗体D 12（IgM）揭示了胎粪中的一种抗原。该抗原是一种热不稳定物质，相对分子量约为400 - 600 kD。用神经氨酸酶处理组织后，MAb D 12在组织切片上的反应被阻断，而用高碘酸钠处理组织后反应增强。在胎儿和成人结肠的杯状细胞以及气管和支气管的类似细胞中发现了抗原D 12。
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