Feindel W, Rasmussen T
Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, Quebec, Canada.
Can J Neurol Sci. 1991 Nov;18(4 Suppl):603-5. doi: 10.1017/s0317167100032807.
The evidence for the role of the amygdala in temporal lobe seizures is supported by this follow-up (2-20 years) of 100 patients who were treated surgically by excision of the antero-lateral temporal cortex, most or all of the amygdala and minimal resection of the hippocampus. The findings showed 53 patients seizure-free or with rare or occasional seizures, 10 patients with marked seizure reduction and 37 with moderate or less reduction of seizures. The results are the same as in another 100 patients where, in addition, half or more of the hippocampus was resected.
对100例接受手术治疗的患者进行了此次随访（2至20年），这些患者接受了前外侧颞叶皮质切除、大部分或全部杏仁核切除以及少量海马体切除，这为杏仁核在颞叶癫痫中所起作用的证据提供了支持。研究结果显示，53例患者无癫痫发作或仅有罕见或偶尔发作，10例患者癫痫发作显著减少，37例患者癫痫发作减少程度为中度或更低。另外100例患者的结果与之相同，在这些患者中，除上述手术外，还切除了一半或更多的海马体。
