Science. 1966 Jul 15;153(3733):303-5. doi: 10.1126/science.153.3733.303.
In female rats, the incorporation of sodium C(14)-formate into mammary gland RNA decreases immediately after a singlefeeding of 20 milligrams of 7,12-dimethylbenz[a] anthracene. In males, there is a gradual increase in the incorporation. In castrated rats, the decrease or increase of C(14)-formate incorporation is dependent on the presence of estrogen or androgen, respectively.
在雌性大鼠中,在单次喂食 20 毫克 7,12-二甲基苯并[a]蒽后,[14C]甲酸钠掺入乳腺 RNA 的情况会立即减少。在雄性大鼠中,[14C]甲酸钠掺入的情况则逐渐增加。在去势大鼠中,[14C]甲酸钠掺入的减少或增加取决于是否存在雌激素或雄激素。