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[高压氧疗对心脏直视手术中心脏血液动力学及肺氧合功能的影响]

[Effect of hyperbaric oxygenation on central hemodynamics and oxygenating function of the lungs in open-heart surgery].

作者信息

Rodionov V V, Abbakumov V V, Efuni S N, Kharitonov S A, Nurpeisov A Z

出版信息

Fiziol Zh (1978). 1991 Jul-Aug;37(4):52-7.

PMID:1778255
Abstract

The dynamics of some oxygenating pulmonary function (OPF) indices has been studied in 33 patients with coronary cardiac disease and rheumatic lesions of cardiac valves 4-6 hours after surgery in response to a single hyperbaric oxygenation (HBO) session (1.5 ata, 45 min) in the immediate postoperative period. It is found that in the presence of slight or, on the contrary, pronounced arterial hypoxemia, no significant negative OPF changes were observed. At the same time, a temporary increase in the alveolo-arterial gradient has been found in some patients. The comparison of data on the systemic blood flow with the OPF indices permits suggesting the prevalent role of the membrane component in a PaO2 decrease in patients after using assisted circulation.

摘要

对33例冠心病和心脏瓣膜风湿性病变患者术后4 - 6小时进行单次高压氧治疗(1.5 ata,45分钟)后,研究了一些氧合肺功能(OPF)指标的动态变化。结果发现,无论是存在轻度还是相反的明显动脉低氧血症,均未观察到OPF有明显的负面变化。同时,部分患者的肺泡 - 动脉氧分压差出现了暂时升高。将全身血流数据与OPF指标进行比较,提示在使用辅助循环后的患者中,膜成分在动脉血氧分压降低中起主要作用。

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