Mamon L A, Barabanova L V
Genetika. 1991 Sep;27(9):1541-6.
Frequency and localization of spontaneous and induced by high temperature (37 degrees C) recessive lethal mutations in X-chromosome of females belonging to the 1(1) ts 403 strain defective in synthesis of heat-shock proteins (HSP) were studied. No differences in frequencies of both spontaneous and induced lethals between 1(1) ts 403 and control strain were found, thus implying that the disturbances in HSP synthesis have no effect on this process in oocytes of Drosophila melanogaster females. Surprisingly, distribution of spontaneous and induced lethals along the X-chromosome of 1(1) ts 403 strain appeared to be non-random: they primarily are located in its distal portion (1-44 cM of genetic map or in I-II sections of the Bridges cytogenetic map). This correlates with non-random distribution of mobile elements in the X-chromosome of D. melanogaster (Leibovich, 1990).
研究了属于1(1)ts 403品系的雌性果蝇X染色体中自发的以及由高温（37摄氏度）诱导的隐性致死突变的频率和定位，该品系在热休克蛋白（HSP）合成方面存在缺陷。未发现1(1)ts 403品系与对照品系在自发和诱导致死频率上存在差异，这意味着HSP合成的紊乱对黑腹果蝇雌性卵母细胞中的这一过程没有影响。令人惊讶的是，1(1)ts 403品系X染色体上自发和诱导致死突变的分布似乎是非随机的：它们主要位于其远端部分（遗传图谱的1-44 cM或布里奇斯细胞遗传图谱的I-II区段）。这与黑腹果蝇X染色体中移动元件的非随机分布相关（莱博维奇，1990年）。
