Brodersen M, Folger W
Med Klin. 1976 Apr 9;71(15):621-8.
Seroconversion was observed in 6 patients, indicating an infection with hepatitis virus B. All of these patients had been hospitalized with HBAg-positive persons a few weeks before, 5 of them because of acute hepatitis type A. While seroconversion was followed by acute hepatitis in 4 cases, the infection remained clinically silent in the other two patients. The second periods of illness were no attacks of relapsing hepatitis type A, as was indicated by HBAg. Vice versa superinfection of hepatitis B-patients with hepatitis virus A may occur, as is discussed in another case. Acute hepatitis is often transmitted in hospitals. Infective routes are discussed and means are described, by which is attempted, to reduce the incidence of hospital-acquired hepatitis.
6例患者出现血清学转换,提示感染乙型肝炎病毒。所有这些患者几周前曾与乙肝表面抗原(HBAg)阳性者一起住院,其中5例是因为甲型急性肝炎。4例患者血清学转换后发生急性肝炎,另外2例患者感染在临床上未表现出症状。第二发病期并非甲型复发性肝炎发作,乙肝表面抗原检测结果表明了这一点。反之,如另一病例所讨论的,乙型肝炎患者可能发生甲型肝炎病毒的重叠感染。急性肝炎常在医院传播。文中讨论了感染途径并描述了所尝试采用的方法,以降低医院获得性肝炎的发病率。