Atkins Louise, Fallowfield Lesley J
Cancer Research UK Psychosocial Oncology Group, Brighton and Sussex Medical School, University of Sussex, Brighton, UK.
Menopause Int. 2007 Sep;13(3):103-9. doi: 10.1258/175404507781605578.
To determine the effect of cancer, cancer risk, menopausal status and psychological factors on sexual activity as measured by Fallowfield's Sexual Activity Questionnaire (FSAQ).
Five groups of women completed the FSAQ: 1451 healthy women who were participating in an ovarian cancer screening trial; 488 healthy women at increased risk of breast cancer who were participating in a chemoprevention trial; 154 healthy women at increased risk of breast cancer who had been offered risk-reducing surgery; 117 women with advanced ovarian cancer; and a healthy non-study sample of 162 women.
There were significant between-group differences regarding age (F=1373.79, P<0.01) and the proportion of women who were sexually active (chi2(4)=212.62, P<0.01) (more younger women reported being sexually active). The most commonly cited reason for sexual inactivity was the absence of a partner. In relation to their sexual activity, women with ovarian cancer reported less pleasure (F=18.27, P<0.01), more discomfort (F=21.33, P<0.01) and less frequency (F=200.01, P<0.01) than the other groups. Premenopausal women reported more pleasure (t=4.41, P<0.01), less discomfort (t=11.79, P<0.01) and greater frequency of sexual activity (t=8.58, P<0.01) than postmenopausal women. Psychological morbidity was associated with decreased pleasure in sexual activity among the women with an elevated risk of cancer - that is, those participating in the chemoprevention trial (t=4.20, P<0.01) and those offered risk-reducing surgery (t=3.32, P<0.01).
The FSAQ is a useful tool for measuring sexual activity in women with cancer and women at a normal or increased risk of developing cancer. Age, cancer, psychological distress and menopausal status affect sexual activity in these groups of women and should be considered in future investigations.
通过法洛菲尔德性活动问卷（FSAQ）来确定癌症、癌症风险、绝经状态和心理因素对性活动的影响。
五组女性完成了FSAQ：1451名参与卵巢癌筛查试验的健康女性；488名参与化学预防试验、患乳腺癌风险增加的健康女性；154名已接受降低风险手术、患乳腺癌风险增加的健康女性；117名晚期卵巢癌女性；以及162名健康非研究样本女性。
在年龄（F = 1373.79，P < 0.01）和性活跃女性比例方面（卡方(4)=212.62，P < 0.01）存在显著组间差异（更多年轻女性报告有性活动）。性不活跃最常见的原因是没有伴侣。与其他组相比，卵巢癌女性在性活动方面报告的愉悦感更少（F = 18.27，P < 0.01）、不适感更多（F = 21.33，P < 0.01）且频率更低（F = 200.01，P < 0.01）。绝经前女性报告的愉悦感更多（t = 4.41，P < 0.01）、不适感更少（t = 11.79，P < 0.01）且性活动频率更高（t = 8.58，P < 0.01），高于绝经后女性。心理疾病与癌症风险升高的女性（即参与化学预防试验的女性（t = 4.20，P < 0.01）和接受降低风险手术的女性（t = 3.32，P < 0.01））性活动愉悦感降低有关。
FSAQ是测量癌症女性以及患癌症风险正常或增加的女性性活动的有用工具。年龄、癌症、心理困扰和绝经状态会影响这些女性群体的性活动，在未来研究中应予以考虑。
