急性恶性疟中的脂质过氧化作用。
Lipid peroxidation in acute falciparum malaria.
作者信息
Rath R N, Panigrahi N, Das B K, Das P K
机构信息
Department of Medicine, SCB Medical College, Cuttack.
出版信息
Indian J Med Res. 1991 Sep;93:303-5.
Lipid peroxidation was assessed by measuring malondialdehyde (MDA) in 30 patients with falciparum malaria and 20 controls (10 healthy adults and 10 patients of vivax malaria). Mean serum MDA was 0.96 +/- 0.38 nmol/ml, 1.1 +/- 0.17 nmol/ml and 2.9 +/- 1.1 nmol/ml in healthy controls, disease controls and falciparum malaria patients, respectively. Levels were significantly high (P less than 0.001) in patients with falciparum malaria. Higher values were associated with more number of complications and deaths.
通过测量丙二醛（MDA）评估30例恶性疟患者和20例对照者（10名健康成年人和10例间日疟患者）的脂质过氧化情况。健康对照者、疾病对照者和恶性疟患者的血清MDA均值分别为0.96±0.38纳摩尔/毫升、1.1±0.17纳摩尔/毫升和2.9±1.1纳摩尔/毫升。恶性疟患者的MDA水平显著升高（P<0.001）。较高的值与更多的并发症和死亡相关。
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