玻璃体内注射贝伐单抗作为疑似眼组织胞浆菌病综合征相关脉络膜新生血管的初始治疗方法。
Intravitreal bevacizumab as initial treatment for choroidal neovascularization associated with presumed ocular histoplasmosis syndrome.
作者信息
Adán Alfredo, Navarro Manuel, Casaroli-Marano Ricardo P, Ortiz Santiago, Molina Juan José
机构信息
Department of Ophthalmology, Hospital Clinic de Barcelona, Universidad de Barcelona, Calle Villarroel 170, 08036 Barcelona, Spain.
出版信息
Graefes Arch Clin Exp Ophthalmol. 2007 Dec;245(12):1873-5. doi: 10.1007/s00417-007-0637-y. Epub 2007 Sep 5.
PURPOSE
To report a case of juxtafoveal choroidal neovascularization in a patient with presumed ocular histoplasmosis syndrome (POHS) who was treated with intravitreal injection of bevacizumab (Avastin) as initial treatment.
METHODS
A 23-year-old woman with POHS presented with sudden dimness of vision and metamorphopsia in the right eye. The patient was examined with ophthalmoscopy, fluorescein angiography, and optical coherence tomography (OCT).
RESULTS
Fundus examination, fluorescein angiography, and OCT of the right eye revealed a juxtafoveal choroidal neovascularization. Intravitreal injection of bevacizumab was performed with a postoperative improvement of visual acuity and resolution of the distortion.
CONCLUSIONS
This case report describes a case of juxtafoveal choroidal neovascularization associated with POHS that responded remarkably well to intravitreal injection of bevacizumab.
目的
报告一例疑似眼组织胞浆菌病综合征（POHS）患者发生的黄斑旁脉络膜新生血管，该患者接受玻璃体内注射贝伐单抗（阿瓦斯汀）作为初始治疗。
方法
一名患有POHS的23岁女性右眼突然视力模糊并出现视物变形。对该患者进行了检眼镜检查、荧光素血管造影和光学相干断层扫描（OCT）。
结果
右眼的眼底检查、荧光素血管造影和OCT显示黄斑旁脉络膜新生血管。进行了玻璃体内注射贝伐单抗，术后视力提高，视物变形症状消失。
结论
本病例报告描述了一例与POHS相关的黄斑旁脉络膜新生血管，对玻璃体内注射贝伐单抗反应显著良好。
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