Zappa Luis, Sugarbaker Paul H
Washington Cancer Institute, Washington, District of Columbia 20010, USA.
J Surg Oncol. 2007 Dec 1;96(7):619-23. doi: 10.1002/jso.20884.
Compartment syndrome is seen in patients who have ischemic damage to muscle that is contained within a fascial compartment. A pathologic cycle is initiated when tissue injury produces swelling and compromises muscle perfusion. Patients undergoing cytoreductive surgery combined with intraperitoneal chemotherapy are required to be in the lithotomy position for many hours. Compartment syndrome can develop necessitating fasciotomy.
In a study of 473 operative procedures to perform cytoreductive surgery and intraperitoneal chemotherapy, eight patients required fasciotomy on an emergency basis to treat compartment syndrome and were recorded in a prospective database over a 4-year time period.
During the hospitalization five of the eight patients developed venous thrombotic complications. In order to prevent movement of the patient on the operating table during steep Trendelenburg position, shoulder braces were used in the subsequent 250 patients and no episodes of compartment syndrome occurred.
Compartment syndrome in patients undergoing cytoreductive surgery may be related to changes in position on the operating table induced by steep Trendelenburg position. Minimizing this change in position has reduced the likelihood of developing Compartment syndrome.
筋膜间隔综合征见于筋膜间隔内肌肉发生缺血性损伤的患者。当组织损伤导致肿胀并损害肌肉灌注时,会启动一个病理循环。接受减瘤手术联合腹腔内化疗的患者需要长时间处于截石位。筋膜间隔综合征可能发展,需要进行筋膜切开术。
在一项对473例进行减瘤手术和腹腔内化疗的手术操作的研究中,8例患者因紧急治疗筋膜间隔综合征而需要进行筋膜切开术,并在4年的时间里记录于一个前瞻性数据库中。
在住院期间,8例患者中有5例出现静脉血栓并发症。为了防止患者在深头低脚高位时在手术台上移动,在随后的250例患者中使用了肩部固定带,未发生筋膜间隔综合征病例。
接受减瘤手术的患者发生筋膜间隔综合征可能与深头低脚高位引起的手术台上体位变化有关。尽量减少这种体位变化降低了发生筋膜间隔综合征的可能性。