Wiegersma S, de Jong E, van Dieren M
University of Utrecht, Vakgroep Psychonomie, The Netherlands.
J Clin Exp Neuropsychol. 1991 Nov;13(6):847-53. doi: 10.1080/01688639108405102.
Frontal-lobe dysfunction of alcoholic Korsakoff patients was studied by presenting four tasks requiring short-term retention, as well as different degrees and types of control. Digit span forward was considered a measure of passive short-term retention; missing scan measures memory search and comparison, in addition to retention; and two subjective ordering tasks measure active generation of responses in addition to the processes in the other two tasks. The results showed no evidence of reduced performance for any of these tasks, when compared with performance of control subjects. The hypothesis that Korsakoff patients have a frontal-lobe dysfunction in addition to their amnesia needs some qualification because of these results: Frontal-lobe function specific to the ordering of verbal responses seems to be intact in Korsakoff patients.
