激素活性卵巢肿瘤的组织化学
Histochemistry of hormonally active ovarian tumors.
作者信息
Kedzia H, Pisarski T
出版信息
Pol Med Sci Hist Bull (1973). 1975 Mar-Apr;15(2):229-39.
Thirty-five ovarian tumors were examined (7 granulosa-cell tumors, 2 thecomas, 4 dysgerminomas, 6 mucinous cystadenomas, 10 serous cystadenomas, 2 adenocarcinomas, 3 Krukenberg tumors and 1 early embryonic tumor). The granulosa-cell tumors showed high activity of alpha-glycerophosphate dehydrogenase, and the changed cells of their stroma--that of glucose-6 phosphate and isocitrate dehydrogenases. The activity of the latter enzymes was striking also in thecomas. Dysgerminomas showed high alkaline phosphatase, acid phosphatase and nonspecific esterase activities. The authors emphasize the role of stromal cells in the hormonal activity of ovarian neoplasms.
对35个卵巢肿瘤进行了检查（7个颗粒细胞瘤、2个卵泡膜瘤、4个无性细胞瘤、6个黏液性囊腺瘤、10个浆液性囊腺瘤、2个腺癌、3个库肯勃瘤和1个早期胚胎性肿瘤）。颗粒细胞瘤显示α-甘油磷酸脱氢酶活性高，其基质的变化细胞——葡萄糖-6-磷酸和异柠檬酸脱氢酶的活性变化。后一种酶的活性在卵泡膜瘤中也很显著。无性细胞瘤显示高碱性磷酸酶、酸性磷酸酶和非特异性酯酶活性。作者强调了基质细胞在卵巢肿瘤激素活性中的作用。
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