Tart R P, Li K C, Storm B L, Rolfes R J, Ang P G
Department of Radiology, University of Florida College of Medicine, Gainesville 32610.
Magn Reson Imaging. 1991;9(4):559-68. doi: 10.1016/0730-725x(91)90043-l.
We compared the effectiveness of 1 mM Geritol, 12% corn oil emulsion, Kaolin-pectin, single contrast oral barium sulfate, and effervescent granules as enteric magnetic resonance imaging (MRI) contrast agents. Five volunteers were recruited. Each volunteer ingested for examinations, separated by at least one week, either 500 ml of each of the liquid preparations or two packets of the CO2 granules (producing 400 ml of CO2 per packet). Abdominal MR images were then obtained using a 1.5 T Magnetom imager and SE 550/22, SE 2000/45/90 and FISP 40/18/40 degrees pulse sequences. The oil emulsions were best tolerated. Barium sulfate caused the greatest amount of nausea, followed by Geritol and Kaolin-pectin. With FISP 40/18/40 degrees, 60%-80% of the small bowel was well delineated using oil emulsion, Kaolin-pectin, or barium sulfate. We conclude that oil emulsion was by far the best enteric MR contrast agent in our study. Good delineation of the small bowel and pancreas can be achieved using oil emulsion and gradient echo pulse sequences. The lack of side-effects and the excellent taste make it highly acceptable to human subjects.
我们比较了1 mM的健尔力（Geritol）、12%玉米油乳剂、高岭土果胶、单对比口服硫酸钡和泡腾颗粒作为肠道磁共振成像（MRI）造影剂的效果。招募了5名志愿者。每位志愿者分别服用每种液体制剂500毫升或两包二氧化碳颗粒（每包产生400毫升二氧化碳）进行检查，检查间隔至少一周。然后使用1.5 T Magnetom成像仪及SE 550/22、SE 2000/45/90和FISP 40/18/40度脉冲序列获取腹部MR图像。油乳剂的耐受性最佳。硫酸钡导致的恶心感最强，其次是健尔力和高岭土果胶。使用FISP 40/18/40度序列时，60% - 80%的小肠使用油乳剂、高岭土果胶或硫酸钡可得到良好勾勒。我们得出结论，在我们的研究中，油乳剂是迄今为止最佳的肠道MR造影剂。使用油乳剂和梯度回波脉冲序列可实现小肠和胰腺的良好勾勒。其无副作用且味道极佳，使其非常受人体受试者欢迎。
