Erlander M G, Tobin A J
Neuroscience Program, University of California, Los Angeles 90024.
Neurochem Res. 1991 Mar;16(3):215-26. doi: 10.1007/BF00966084.
Studies of the GABA-synthetic enzyme glutamate decarboxylase (glutamic acid decarboxylase; GAD; E.C.4.1.1.15) began in 1951 with the work of Roberts and his colleagues. Since then, many investigators have demonstrated the structural and functional heterogeneity of brain GAD. At least part of this heterogeneity derives from the existence of two GAD genes.
对γ-氨基丁酸合成酶谷氨酸脱羧酶(谷氨酸脱羧酶;GAD;酶学委员会编号4.1.1.15)的研究始于1951年罗伯茨及其同事的工作。从那时起,许多研究人员已经证明了脑GAD的结构和功能异质性。这种异质性至少部分源于两个GAD基因的存在。