Research note: naloxone inhibits drinking in the chick induced by angiotensin II.

Subcutaneous injection of Angiotensin II (AII) induces a rapid increase in water intake in the chick. These studies were designed to determine whether this response was mediated through the opioid system. Injection of AII stimulated a rapid increase in water intake. Administration of naloxone, an opioid antagonist, attenuated AII-induced drinking in the chick. These data would indicate that the opioids may be involved in the drinking response elicited by AII.