Patterson Jeremy A, Pitetti Kenneth H, Young Kaelin C, Goodman William F, Farhoud Hussam
Department of Kinesiology and Sports Studies, Wichita State University, and Cyprus Heart, Wichita, KS 67260-0016, USA.
Med Sci Sports Exerc. 2007 Sep;39(9):1447-51. doi: 10.1249/mss.0b013e318074d3d7.
It has been well documented that for heart transplant recipients (HTR), posttransplantation physical work capacity (PWC) normally does not exceed 60% of the value for healthy age-matched controls. Few, if any, studies have undertaken posttransplantation PWC measurements of well-conditioned individuals (i.e., PWC>300 W).
A 37-yr-old professionally trained male cyclist suffered an acute myocardial infarction (AMI) immediately after a road race and received a heart transplant (HT) 4 months after the AMI. The participant resumed training 1 month after surgery and underwent a maximal exercise test 6 months after surgery. Peak PWC (33.8 mL.kg(-1).min(-1), 250 W) was 92% of the age-predicted maximum, and peak heart rate (165 bpm) was 96% of his known maximum. These results were similar to the participants in a study who had been training regularly for 36+/-24 months before testing, and PWC evaluations occurred 43+/-12 months after HT.
Results suggest that 1) lifestyle before HT may positively affect posttransplantation PWC, 2) exercise capacity was not limited by chronotropic incompetence, and 3) a more aggressive approach to HT recovery could be applied to HTR with similar activity histories.
有充分文献记载,对于心脏移植受者(HTR),移植后的体力工作能力(PWC)通常不超过年龄匹配的健康对照者的60%。几乎没有研究对身体状况良好的个体(即PWC>300W)进行移植后的PWC测量。
一名37岁经过专业训练的男性自行车运动员在一场公路赛后立即发生急性心肌梗死(AMI),并在AMI后4个月接受了心脏移植(HT)。参与者在术后1个月恢复训练,并在术后6个月进行了最大运动测试。峰值PWC(33.8 mL·kg⁻¹·min⁻¹,250W)为年龄预测最大值的92%,峰值心率(165次/分钟)为其已知最大值的96%。这些结果与一项研究中的参与者相似,该研究中的参与者在测试前已定期训练36±24个月,PWC评估在HT后43±12个月进行。
结果表明,1)HT前的生活方式可能对移植后的PWC产生积极影响,2)运动能力不受变时性功能不全的限制,3)对于有类似活动史的HTR,可以采用更积极的HT恢复方法。