Hepler R S
Surv Ophthalmol. 1976 Mar-Apr;20(5):350-7. doi: 10.1016/s0039-6257(96)90003-x.
To improve understanding and effectiveness of therapy in optic nerve disease, various causes of so-called optic neuritis should be identified when possible. The clinical characteristics of demyelinating optic neuropathy can be contrasted with those of ischemic optic neuropathy, nutritional optic neuropathy, true optic nerve inflammation (e.g., luetic), optic nerve infiltration with tumor, and compression neuropathy caused by adjacent tumor. Radiologic studies and other means of investigating patients with optic neuritis are reviewed. Arguments in favor of, and against, treatment of presumed demyelinating optic neuritis are presented along with representative corticosteroid treatment regimens. The natural tendency toward spontaneous improvement of optic neuritis makes the effect of treatment difficult to assess.
为提高对视神经疾病治疗的理解及治疗效果，应尽可能明确所谓视神经炎的各种病因。脱髓鞘性视神经病变的临床特征可与缺血性视神经病变、营养性视神经病变、真性视神经炎症（如梅毒所致）、肿瘤浸润视神经及邻近肿瘤所致压迫性神经病变的临床特征进行对比。本文综述了视神经炎患者的影像学研究及其他检查方法。文中介绍了支持和反对对疑似脱髓鞘性视神经炎进行治疗的观点，并给出了代表性的皮质类固醇治疗方案。视神经炎自然好转的趋势使得治疗效果难以评估。
