Science. 1968 Sep 13;161(3846):1155-7. doi: 10.1126/science.161.3846.1155.
Allergic encephalomyelitis was produced in rats by passive transfer of lymph node cells from donors immunized intradernmally with nleural tissute or an encephalitogenic basic protein pluts adjulvants. The same basic protein, injected intravenously into the recipients before or after transfer of lymph node cells, prevented the disease. Even established lesions were reversed. Inhibition by basic protein was specific for encephalomyelitis; it had no effect onz passive transfer of allergic adrenalitis.
过敏性脑脊髓炎可通过被动转移皮内免疫神经组织或致脑炎碱性蛋白加佐剂的供体动物淋巴结细胞在大鼠中产生。在转移淋巴结细胞之前或之后将同一碱性蛋白静脉内注射给受者,可预防疾病。甚至已确立的病变也可逆转。碱性蛋白的抑制作用是针对脑脊髓炎的,对过敏性肾上腺炎的被动转移没有影响。