Stenager E, Jensen K
Clinical Neuro-Psychiatric Research Unit, Odense University Hospital, Denmark.
Acta Neurol Belg. 1991;91(5):296-302.
In a cross-sectional study of 299 MS patients 22 have had fractures and of these 17 after onset of MS. The fractures most frequently involved the femoral neck and trochanter (41%). Three patients had had more than one fracture. Only 1 patient had osteoporosis. The percentage of fractures increased with increasing age and disease duration. Among 34 deceased MS patients 4 had had fractures. These findings are discussed in relation to physical and cognitive impairment in MS. A case-control study is recommended.
在一项对299例多发性硬化症（MS）患者的横断面研究中，22例曾发生骨折，其中17例在MS发病后发生骨折。骨折最常累及股骨颈和转子（41%）。3例患者发生过不止一次骨折。只有1例患者患有骨质疏松症。骨折的百分比随年龄和病程的增加而增加。在34例已故的MS患者中，4例曾发生骨折。这些发现结合MS患者的身体和认知障碍进行了讨论。建议进行病例对照研究。
