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[实验中单次玻璃体内注射头孢噻肟和庆大霉素治疗眼内炎]

[Treatment of endophthalmitis with a single intravitreous administration of cefotaxime and gentamicin in an experiment].

作者信息

Moroz A F, Radkevich S A, Glinchuk Ia I, Gusev Iu A

出版信息

Antibiot Khimioter. 1991 Sep;36(9):25-7.

PMID:1781705
Abstract

Experimental endophthalmitis was treated with single intravitreous administrations of cefotaxime (claforan) and gentamicin. It was found that a single administration of cefotaxime to the vitreous body prevented development of endophthalmitis in rabbits previously infected with Staphylococcus aureus, E. coli and Pseudomonas aeruginosa. Vitrectomy in the treatment of endophthalmitis was shown to be promising and provide satisfactory anatomical and functional results.

摘要

实验性眼内炎采用头孢噻肟(头孢氨噻肟)和庆大霉素单次玻璃体内给药进行治疗。结果发现,向玻璃体单次注射头孢噻肟可预防先前感染金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌的家兔发生眼内炎。玻璃体切除术在治疗眼内炎方面显示出前景,并能提供令人满意的解剖和功能结果。

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