Science. 1965 Jun 25;148(3678):1746-7. doi: 10.1126/science.148.3678.1746.
Human cells altered by infection with the "lipovirus," a transmissible cytopathic agent, are highly resistant to ionizing radiation. Whereas about 500 roentgens will inhibit cell multiplication in normal cells, more than 500,000 roentgens are required to produce a similar effect in the altered cells. This gross change in cellular radiosensitivity may provide a useful system for studying in vitro the mechanisms of inhibition of cell division by radiation.
受“脂病毒”(一种可传播的细胞病变剂)感染的人体细胞对电离辐射具有很强的抵抗力。正常细胞中约 500 伦琴即可抑制细胞增殖,而在受感染的细胞中则需要超过 500,000 伦琴才能产生类似的效果。这种细胞放射敏感性的巨大变化可能为体外研究辐射抑制细胞分裂的机制提供一个有用的系统。