Older R A, Miller J P, Jackson D C, Johnsrude I S, Thompson W M
AJR Am J Roentgenol. 1976 May;126(5):1039-45. doi: 10.2214/ajr.126.5.1039.
Decreased renal function following arteriography is much more common than is currently realized. Steps to detect this failure are necessary, especially in high risk patients, so that stressful situations such as surgery can be avoided. A recently performed prospective random study of 100 patients undergoing angiography demonstrated a 10% incidence of renal failure. Those patients most at risk had preexisting renal disease as indicated by an elevated serum creatinine and/or cardiovascular disease severe enough to require digoxin, diuretics, or nitroglycerin. No cases of renal failure occurred in the absence of one or both of these processes. The likelihood of postangiographic renal failure was unrelated to the quantity of contrast as measured either by total volume or per kilogram body weight.
动脉造影术后肾功能下降比目前所认识到的更为常见。检测这种功能衰竭的措施是必要的，尤其是在高危患者中，以便避免诸如手术等应激情况。最近对100例接受血管造影的患者进行的一项前瞻性随机研究表明，肾衰竭的发生率为10%。那些风险最高的患者存在先前的肾脏疾病，表现为血清肌酐升高和/或严重到需要使用地高辛、利尿剂或硝酸甘油的心血管疾病。在没有这两种情况之一或两者都没有的情况下，没有发生肾衰竭病例。血管造影术后肾衰竭的可能性与通过总体积或每千克体重测量的造影剂用量无关。
