Bemelmans Wanda, van Baal Pieter, Wendel-Vos Wanda, Schuit Jantine, Feskens Edith, Ament Andre, Hoogenveen Rudolf
National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Prev Med. 2008 Feb;46(2):127-32. doi: 10.1016/j.ypmed.2007.07.029. Epub 2007 Aug 3.
To gain insight in realistic policy targets for overweight at a population level and the accompanying costs. Therefore, the effect on overweight prevalence was estimated of large scale implementation of a community intervention (applied to 90% of general population) and an intensive lifestyle program (applied to 10% of overweight adults), and costs and cost-effectiveness were assessed.
Costs and effects were based on two Dutch projects and verified by similar international projects. A markov-type simulation model estimated long-term health benefits, health care costs and cost-effectiveness.
Combined implementation of the interventions--at the above mentioned scale--reduces prevalence rates of overweight by approximately 3 percentage points and of physical inactivity by 2 percentage points after 5 years, at a cost of 7 euros per adult capita per year. The cost-effectiveness ratio of combined implementation amounts to euro 6000 per life-year gained and euro 5700 per QALY gained (including costs of unrelated diseases in life years gained). Sensitivity analyses showed that these ratios are quite robust.
A realistic policy target is a decrease in overweight prevalence of three percentage points, compared to a situation with no interventions. In reality, large scale implementation of the interventions may not counteract the expected upward trends in The Netherlands completely. Nonetheless, implementation of the interventions is cost-effective.
深入了解人群层面超重的现实政策目标及相应成本。因此,估计了大规模实施社区干预措施(应用于90%的普通人群)和强化生活方式项目(应用于10%的超重成年人)对超重患病率的影响,并评估了成本和成本效益。
成本和效果基于两个荷兰项目,并通过类似的国际项目进行验证。一个马尔可夫类型的模拟模型估计了长期健康效益、医疗保健成本和成本效益。
按照上述规模联合实施干预措施,5年后超重患病率降低约3个百分点,身体活动不足患病率降低2个百分点,人均每年成本为7欧元。联合实施的成本效益比为每获得一个生命年6000欧元,每获得一个质量调整生命年5700欧元(包括获得生命年中无关疾病的成本)。敏感性分析表明这些比率相当稳健。
一个现实的政策目标是与不进行干预的情况相比,超重患病率降低3个百分点。实际上,大规模实施这些干预措施可能无法完全抵消荷兰预期的上升趋势。尽管如此,实施这些干预措施具有成本效益。