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光学相干断层扫描在妇科中的作用和价值

[The role and value of optical coherence tomography in gynecology].

作者信息

Ascencio M, Collinet P, Cosson M, Mordon S

机构信息

Clinique de gynécologie, hôpital Jeanne-de-Flandre, avenue Eugène-Avinée, 59037 Lille cedex, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2007 Dec;36(8):749-55. doi: 10.1016/j.jgyn.2007.07.005. Epub 2007 Sep 5.

Abstract

Optical coherence tomography is one of the most important technological progress of the last ten years in the field of medical imaging. It is similar to ultrasound imaging except that it uses properties of light instead of ultrasound. Optical coherence tomography provides images of tissue structure, and at a cellular level, in situ, in real time, with much better spatial resolution than ultrasound and without removal of tissue (optical biopsy). Using optical coherence tomography in combination with catheters or endoscopes may enable the imaging of internal organs as the cervix, the uterine tissue and the ovary. The use of optical coherence tomography in the gynecological field is still experimental and is mainly about the in vitro and in vivo diagnosis of cervical dysplasia, cervical cancer, ovary cancer, endometrial cancer and endometriosis. We aim to present the principles of optical coherence tomography and to expose the main ways of research and the future and potential clinical applications of this technique in gynecology.

摘要

光学相干断层扫描是医学成像领域过去十年中最重要的技术进展之一。它与超声成像类似,只是它利用的是光的特性而非超声。光学相干断层扫描能够在细胞水平上原位实时提供组织结构图像,其空间分辨率比超声更好,且无需切除组织(光学活检)。将光学相干断层扫描与导管或内窥镜结合使用,可能实现对子宫颈、子宫组织和卵巢等内部器官的成像。光学相干断层扫描在妇科领域的应用仍处于实验阶段,主要用于宫颈发育异常、宫颈癌、卵巢癌、子宫内膜癌和子宫内膜异位症的体外和体内诊断。我们旨在介绍光学相干断层扫描的原理,并阐述该技术在妇科领域的主要研究途径以及未来潜在的临床应用。

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