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法国早期直肠癌腔内接触性X线放射治疗的经验。

French experience with contact X-ray endocavitary radiation for early rectal cancer.

作者信息

Gerard J P, Chapet O, Ortholan C, Benezery K, Barbet N, Romestaing P

机构信息

Department of Radiation Oncology, Centre Antoine Lacassagne, Nice, France.

出版信息

Clin Oncol (R Coll Radiol). 2007 Nov;19(9):661-73. doi: 10.1016/j.clon.2007.07.009. Epub 2007 Sep 5.

Abstract

This paper is an overview of the French experience with contact X-ray radiation for rectal cancer. The analysis was mainly carried out on 50 years of experience in Lyon or since 1980 in the Centre Hospitalier Universitaire Lyon Sud. The results obtained in Dijon and Nancy are also reported. In early rectal cancer, contact X-ray radiation can play an important role in three different situations: (1) small T1 less than 2 cm: adjuvant contact X-ray radiotherapy after local excision; (2) T2 N0 or large T1: first-line contact X-ray radiotherapy combined with external beam radiotherapy (+/- chemotherapy) followed by surgery (anterior resection or local excision); (3) early T3 N0 in frail patients: the same approach as for T2 N0 with, in case of clinical complete response, local excision or follow-up.

摘要

本文是对法国直肠癌接触性X线辐射治疗经验的概述。分析主要基于里昂50年的经验,或自1980年以来里昂南大学医院中心的经验。同时也报告了第戎和南锡所取得的结果。在早期直肠癌中,接触性X线辐射在三种不同情况下可发挥重要作用:(1)小于2 cm的小T1期:局部切除术后辅助接触性X线放射治疗;(2)T2 N0期或大T1期:一线接触性X线放射治疗联合外照射放疗(±化疗),随后进行手术(前切除术或局部切除术);(3)体弱患者的早期T3 N0期:与T2 N0期相同的治疗方法,若临床完全缓解,则进行局部切除或随访。

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