• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

内侧膝关节病行截骨术联合微骨折或磨削术治疗后的关节软骨修复及临床疗效

Repair of articular cartilage and clinical outcome after osteotomy with microfracture or abrasion arthroplasty for medial gonarthrosis.

作者信息

Matsunaga Daigo, Akizuki Shaw, Takizawa Tsutomu, Yamazaki Ikuya, Kuraishi Joji

机构信息

Department of Orthopaedic Surgery and Rehabilitation, Nagano Matsushiro General Hospital, Nagano City, Japan.

出版信息

Knee. 2007 Dec;14(6):465-71. doi: 10.1016/j.knee.2007.06.008. Epub 2007 Sep 5.

DOI:10.1016/j.knee.2007.06.008
PMID:17822904
Abstract

This study compared the healing of articular cartilage and the clinical outcome after osteotomy with or without marrow stimulation microfracture or abrasion arthroplasty for osteoarthritis of the knee. Patients with osteoarthritis of the medial compartment of the knee were divided into a group undergoing high tibial osteotomy alone (HTO group: 37 knees), a group undergoing osteotomy plus microfracture (MF group: 26 knees), and a group undergoing osteotomy plus abrasion arthroplasty (AA group: 51 knees). The extent of cartilage repair was compared at 1 year after surgery by arthroscopy with reference to Outerbridge's classification, while the clinical outcome was compared at 1, 3, and 5 years postoperatively. Second-look arthroscopy revealed better repair of the femoral condylar cartilage in the AA group than the HTO group (p<0.0005) or MF group (p<0.01), with no difference between the HTO and MF groups. Repair of the tibial condylar cartilage was also better in the AA group than the HTO group (p<0.005), but there was no difference between the AA and MF groups or the MF and HTO groups. There were no differences of the clinical outcome between the three groups. In conclusion, repair of articular cartilage at 1 year postoperatively was accelerated by abrasion arthroplasty, but not by microfracture. However, there was no difference of the clinical outcome within 5 years after surgery, so the clinical utility of marrow stimulation techniques was not apparent in this study.

摘要

本研究比较了膝关节骨关节炎患者在进行或不进行骨髓刺激微骨折或磨削关节成形术的截骨术后关节软骨的愈合情况及临床疗效。膝关节内侧间室骨关节炎患者被分为单纯接受高位胫骨截骨术的组(HTO组:37个膝关节)、接受截骨术加微骨折的组(MF组:26个膝关节)和接受截骨术加磨削关节成形术的组(AA组:51个膝关节)。术后1年通过关节镜检查参照Outerbridge分类法比较软骨修复程度,同时在术后1年、3年和5年比较临床疗效。二次关节镜检查显示,AA组股骨髁软骨的修复情况优于HTO组(p<0.0005)或MF组(p<0.01),HTO组和MF组之间无差异。AA组胫骨髁软骨的修复情况也优于HTO组(p<0.005),但AA组和MF组之间以及MF组和HTO组之间无差异。三组之间的临床疗效无差异。总之,术后1年时,磨削关节成形术可加速关节软骨修复,而微骨折则不能。然而,术后5年内临床疗效无差异,因此在本研究中骨髓刺激技术的临床实用性并不明显。

相似文献

1
Repair of articular cartilage and clinical outcome after osteotomy with microfracture or abrasion arthroplasty for medial gonarthrosis.内侧膝关节病行截骨术联合微骨折或磨削术治疗后的关节软骨修复及临床疗效
Knee. 2007 Dec;14(6):465-71. doi: 10.1016/j.knee.2007.06.008. Epub 2007 Sep 5.
2
Cartilage repair procedures associated with high tibial osteotomy in varus knees: clinical results at 11 years' follow-up.与膝内翻患者高位胫骨截骨术相关的软骨修复手术:11年随访的临床结果
Knee. 2014 Mar;21(2):445-50. doi: 10.1016/j.knee.2013.11.013. Epub 2013 Nov 27.
3
Comparison of results of medial opening-wedge high tibial osteotomy with and without subchondral drilling.内侧开口楔形高位胫骨截骨术有无软骨下钻孔的结果比较
Arthroscopy. 2015 Apr;31(4):673-9. doi: 10.1016/j.arthro.2014.11.035. Epub 2015 Jan 27.
4
Chondral resurfacing and high tibial osteotomy in the varus knee: survivorship analysis.内翻膝的软骨修复与高位胫骨截骨术:生存率分析
Am J Sports Med. 2010 Jul;38(7):1420-4. doi: 10.1177/0363546509360403. Epub 2010 Apr 7.
5
Collagen Augmentation Improves the Quality of Cartilage Repair After Microfracture in Patients Undergoing High Tibial Osteotomy: A Randomized Controlled Trial.胶原增强改善高位胫骨截骨术患者微骨折术后软骨修复质量:一项随机对照试验。
Am J Sports Med. 2017 Jul;45(8):1845-1855. doi: 10.1177/0363546517691942. Epub 2017 Mar 10.
6
A prospective, randomized clinical study of osteochondral autologous transplantation versus microfracture for the treatment of osteochondritis dissecans in the knee joint in children.一项关于自体骨软骨移植与微骨折术治疗儿童膝关节剥脱性骨软骨炎的前瞻性随机临床研究。
J Pediatr Orthop. 2009 Oct-Nov;29(7):741-8. doi: 10.1097/BPO.0b013e3181b8f6c7.
7
[Cartilage regeneration after high tibial osteotomy. Results of an arthroscopic study].[高位胫骨截骨术后的软骨再生。一项关节镜研究的结果]
Z Orthop Unfall. 2012 Jun;150(3):272-9. doi: 10.1055/s-0031-1298388. Epub 2012 Jun 22.
8
Second-look arthroscopic assessment of cartilage regeneration after medial opening-wedge high tibial osteotomy.内侧开放楔形胫骨高位截骨术后软骨再生的关节镜下二次评估。
Arthroscopy. 2014 Jan;30(1):72-9. doi: 10.1016/j.arthro.2013.10.008.
9
Arthroscopic second-generation autologous chondrocyte implantation compared with microfracture for chondral lesions of the knee: prospective nonrandomized study at 5 years.关节镜下第二代自体软骨细胞移植与微骨折术治疗膝关节软骨损伤的比较:5年前瞻性非随机研究
Am J Sports Med. 2009 Jan;37(1):33-41. doi: 10.1177/0363546508323256. Epub 2008 Dec 4.
10
Allogenic Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Are More Effective Than Bone Marrow Aspiration Concentrate for Cartilage Regeneration After High Tibial Osteotomy in Medial Unicompartmental Osteoarthritis of Knee.同种异体人脐带血来源间充质干细胞在膝关节内侧单间室骨关节炎胫骨高位截骨术后软骨再生中比骨髓抽吸浓缩物更有效。
Arthroscopy. 2021 Aug;37(8):2521-2530. doi: 10.1016/j.arthro.2021.02.022. Epub 2021 Feb 20.

引用本文的文献

1
Comparison of Clinical, Radiologic, and Arthroscopic Outcomes Between the Microfracture and Microdrilling Techniques for Articular Cartilage Defects in Medial Opening-Wedge High Tibial Osteotomy.内侧开口楔形高位胫骨截骨术中微骨折与微钻孔技术治疗关节软骨缺损的临床、影像学及关节镜检查结果比较
Orthop J Sports Med. 2025 Feb 6;13(2):23259671241309372. doi: 10.1177/23259671241309372. eCollection 2025 Feb.
2
Conversion to Total Knee Arthroplasty After High Tibial Osteotomy: A Systematic Review and Meta-analysis.高位胫骨截骨术后转换为全膝关节置换术:一项系统评价和荟萃分析。
Orthop J Sports Med. 2025 Feb 5;13(2):23259671241310963. doi: 10.1177/23259671241310963. eCollection 2025 Feb.
3
Acellular Particulated Costal Allocartilage Improves Cartilage Regeneration in High Tibial Osteotomy: Data From a Randomized Controlled Trial.
脱细胞颗粒肋软骨异体移植改善高位胫骨截骨术中的软骨再生:一项随机对照试验的数据
Cartilage. 2024 Oct 27:19476035241292321. doi: 10.1177/19476035241292321.
4
Alginate Improves the Chondrogenic Capacity of 3D PCL Scaffolds In Vitro: A Histological Approach.藻酸盐可提高3D聚己内酯支架的体外软骨生成能力:一种组织学方法。
Curr Issues Mol Biol. 2024 Apr 19;46(4):3563-3578. doi: 10.3390/cimb46040223.
5
High tibial osteotomy combined with cartilage restoration: A systematic review of clinical outcomes and prognostic factors.高位胫骨截骨术联合软骨修复:临床结果和预后因素的系统评价
J Clin Orthop Trauma. 2024 Feb 6;50:102360. doi: 10.1016/j.jcot.2024.102360. eCollection 2024 Mar.
6
Adipose-Derived Stromal Vascular Fractions Are Comparable With Allogenic Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells as a Supplementary Strategy of High Tibial Osteotomy for Varus Knee Osteoarthritis.脂肪来源的基质血管成分作为膝内翻性膝骨关节炎高位胫骨截骨术的补充策略,与同种异体人脐带血来源的间充质干细胞相当。
Arthrosc Sports Med Rehabil. 2023 May 29;5(3):e751-e764. doi: 10.1016/j.asmr.2023.04.002. eCollection 2023 Jun.
7
Change in Cartilage Status of Medial Compartment after Open-Wedge High Tibial Osteotomy without Cartilage Regeneration Procedure: Second Look Arthroscopic Assessment.未行软骨再生手术的开放性楔形高位胫骨截骨术后内侧间室软骨状态的变化:二次关节镜评估
Biomedicines. 2023 Jun 5;11(6):1639. doi: 10.3390/biomedicines11061639.
8
Biological intra-articular augmentation for osteotomy in knee osteoarthritis: strategies and results : A systematic review of the literature from the ESSKA Orthobiologics Initiative.膝关节骨关节炎截骨术中的生物关节内增强:策略和结果:ESSKA 矫形生物学会文献的系统回顾。
Knee Surg Sports Traumatol Arthrosc. 2023 Oct;31(10):4327-4346. doi: 10.1007/s00167-023-07469-x. Epub 2023 Jun 18.
9
Isolated Osteotomy Versus Combined Osteotomy and Cartilage Repair for Osteoarthritis or Focal Chondral Defects of the Medial Compartment of the Knee Joint: A Systematic Review.膝关节内侧间室骨关节炎或局灶性软骨缺损的单纯截骨术与联合截骨术及软骨修复术:一项系统评价
Orthop J Sports Med. 2023 May 8;11(5):23259671231162030. doi: 10.1177/23259671231162030. eCollection 2023 May.
10
Typical Complications After Cartilage Repair of the Ankle Using Autologous Matrix-Induced Chondrogenesis (AMIC).使用自体基质诱导软骨生成(AMIC)进行踝关节软骨修复后的典型并发症
Foot Ankle Orthop. 2023 Mar 31;8(1):24730114231164150. doi: 10.1177/24730114231164150. eCollection 2023 Jan.