Schöniger Sandra, Bridger Nicole, Allenspach Karin, Mantis Panagiotis, Rest Joan, Steeves Elizabeth
Department of Pathology and Infectious Diseases, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, United Kingdom.
J Vet Diagn Invest. 2007 Sep;19(5):573-7. doi: 10.1177/104063870701900521.
A 13-year-old female spayed Domestic Shorthair cat presented with a history of right-sided mucopurulent nasal discharge for 18 months. Computed tomography revealed a mass within the right nasal cavity and the right frontal sinus. The animal was euthanized, and a postmortem examination was performed. On macroscopic examination, the right nasal cavity and the right frontal sinus were partially occluded by a soft whitish mass. Microscopically, the mass was composed of well-differentiated plasma cells that were immunopositive for immunoglobulin G and lambda light chains. These findings were consistent with a mature-type sinonasal plasmacytoma. In addition, there was right-sided mucopurulent rhinitis and sinusitis caused by a Pasteurella infection, which probably developed secondary to the sinonasal plasmacytoma. To the authors' knowledge, this is the first report of a sinonasal plasmacytoma in a cat. The present communication shows that feline sinonasal plasmacytomas should be included in the differential diagnosis for tumors located in the upper respiratory tract of cats.
一只13岁已绝育的雌性家养短毛猫,有18个月的右侧黏液脓性鼻分泌物病史。计算机断层扫描显示右侧鼻腔和右侧额窦内有一个肿块。该动物实施安乐死后进行了尸检。大体检查时,右侧鼻腔和右侧额窦被一个柔软的白色肿块部分阻塞。显微镜下,肿块由分化良好的浆细胞组成,这些浆细胞对免疫球蛋白G和λ轻链呈免疫阳性。这些发现符合成熟型鼻窦浆细胞瘤。此外,存在由巴斯德氏菌感染引起的右侧黏液脓性鼻炎和鼻窦炎,这可能是鼻窦浆细胞瘤继发所致。据作者所知,这是猫鼻窦浆细胞瘤的首例报告。本报告表明,猫鼻窦浆细胞瘤应纳入猫上呼吸道肿瘤的鉴别诊断中。