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猫的鼻窦浆细胞瘤

Sinonasal plasmacytoma in a cat.

作者信息

Schöniger Sandra, Bridger Nicole, Allenspach Karin, Mantis Panagiotis, Rest Joan, Steeves Elizabeth

机构信息

Department of Pathology and Infectious Diseases, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, United Kingdom.

出版信息

J Vet Diagn Invest. 2007 Sep;19(5):573-7. doi: 10.1177/104063870701900521.

Abstract

A 13-year-old female spayed Domestic Shorthair cat presented with a history of right-sided mucopurulent nasal discharge for 18 months. Computed tomography revealed a mass within the right nasal cavity and the right frontal sinus. The animal was euthanized, and a postmortem examination was performed. On macroscopic examination, the right nasal cavity and the right frontal sinus were partially occluded by a soft whitish mass. Microscopically, the mass was composed of well-differentiated plasma cells that were immunopositive for immunoglobulin G and lambda light chains. These findings were consistent with a mature-type sinonasal plasmacytoma. In addition, there was right-sided mucopurulent rhinitis and sinusitis caused by a Pasteurella infection, which probably developed secondary to the sinonasal plasmacytoma. To the authors' knowledge, this is the first report of a sinonasal plasmacytoma in a cat. The present communication shows that feline sinonasal plasmacytomas should be included in the differential diagnosis for tumors located in the upper respiratory tract of cats.

摘要

一只13岁已绝育的雌性家养短毛猫,有18个月的右侧黏液脓性鼻分泌物病史。计算机断层扫描显示右侧鼻腔和右侧额窦内有一个肿块。该动物实施安乐死后进行了尸检。大体检查时,右侧鼻腔和右侧额窦被一个柔软的白色肿块部分阻塞。显微镜下,肿块由分化良好的浆细胞组成,这些浆细胞对免疫球蛋白G和λ轻链呈免疫阳性。这些发现符合成熟型鼻窦浆细胞瘤。此外,存在由巴斯德氏菌感染引起的右侧黏液脓性鼻炎和鼻窦炎,这可能是鼻窦浆细胞瘤继发所致。据作者所知,这是猫鼻窦浆细胞瘤的首例报告。本报告表明,猫鼻窦浆细胞瘤应纳入猫上呼吸道肿瘤的鉴别诊断中。

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