Palmer Antony, Bowling Jonathan
Department of Dermatology, Churchill Hospital, Oxford, UK.
Dermatology. 2007;215(3):256-9. doi: 10.1159/000106586.
Juvenile xanthogranuloma (JXG) is the commonest form of non-Langerhans cell histiocytosis and manifests as asymptomatic yellow-red papulonodules that usually occur in childhood and spontaneously regress within a year of formation. The diagnosis may be made by clinical examination alone and confirmed by histology in cases of diagnostic doubt. Here we report the use of dermoscopy in evaluating skin lesions suggestive of JXG. Three patients diagnosed as having JXG in our dermatology department over the last year showed a characteristic orange-yellow 'setting sun' appearance on dermoscopy. We therefore feel that the use of dermoscopy can be extended to include the examination of non-pigmented skin lesions, particularly in paediatric patients.
幼年性黄色肉芽肿(JXG)是最常见的非朗格汉斯细胞组织细胞增生症形式,表现为无症状的黄红色丘疹结节,通常发生于儿童期,形成后一年内可自发消退。仅通过临床检查即可做出诊断,诊断存疑时可通过组织学检查确诊。本文报告了皮肤镜在评估疑似JXG的皮肤病变中的应用。去年在我们皮肤科诊断为JXG的3例患者在皮肤镜检查中呈现出特征性的橙黄色“落日”外观。因此,我们认为皮肤镜的应用可扩展至包括对无色素沉着的皮肤病变的检查,尤其是在儿科患者中。