Park Jung-Woo, Jun Chul-Ho
Department of Chemistry and Centre for Bioactive Molecular Hybrid (CBMH), Yonsei University, Seoul 120-749, Korea.
Org Lett. 2007 Sep 27;9(20):4073-6. doi: 10.1021/ol701909e. Epub 2007 Sep 8.
Highly efficient O-silylation of alcohol with vinylsilane was developed using a catalyst system consisting of (COE)(2)RhCl and HCl. In this reaction, a key intermediate is chlorosilane, generated from vinylsilane and HCl, which can be regenerated in the catalytic cycle. Various alcohols and vinylsilanes were applied to the preparation of silyl ether compounds with this catalyst system.
使用由[(COE)₂RhCl]₂和HCl组成的催化剂体系，实现了醇与乙烯基硅烷的高效O-硅烷化反应。在该反应中，关键中间体是由乙烯基硅烷和HCl生成的氯硅烷，其可在催化循环中再生。利用该催化剂体系，将各种醇类和乙烯基硅烷应用于硅醚化合物的制备。
