Muslahi M A, Ross D M
Department of Clinical Haematology and Bone Marrow Transplantation, Royal Adelaide Hospital, North Terrace, Adelaide, SA, Australia.
Int J Lab Hematol. 2007 Oct;29(5):390-2. doi: 10.1111/j.1365-2257.2006.00845.x.
The clinical presentation of acute myeloid leukaemia is variable. We report a 40-year-old woman who presented with a 1-month history of galactorrhoea with an elevated prolactin level. The blood counts were normal, but she was found to have acute myeloid leukaemia with monocytic differentiation. The serum prolactin level normalized after chemotherapy. In the absence of evidence of CNS involvement, the hyperprolactinaemia is presumed to be a paraneoplastic phenomenon. We discuss the potential mechanism of prolactin production in this case.
急性髓系白血病的临床表现多样。我们报告一名40岁女性,她有1个月的溢乳病史,催乳素水平升高。血常规正常,但她被诊断为伴有单核细胞分化的急性髓系白血病。化疗后血清催乳素水平恢复正常。在没有中枢神经系统受累证据的情况下,高催乳素血症被认为是一种副肿瘤现象。我们讨论了该病例中催乳素产生的潜在机制。