Nuyen J, Spreeuwenberg P M, Van Dijk L, den Bos G A M Van, Groenewegen P P, Schellevis F G
NIVEL, Netherlands Institute for Health Services Research, Utrecht, The Netherlands.
Psychol Med. 2008 Feb;38(2):265-77. doi: 10.1017/S0033291707001298. Epub 2007 Sep 10.
Limited information exists on the relationship between specific chronic somatic conditions and care for co-morbid depression in primary care settings. Therefore, the present prospective, general practice-based study examined this relationship.
Longitudinal data on morbidity, prescribing and referrals concerning 991 patients newly diagnosed with depression by their general practitioner (GP) were analysed. The influence of a broad range of 13 specific chronic somatic conditions on the initiation of any depression care, as well as the prescription of continuous antidepressant therapy for 180 days, was examined. Multilevel logistic regression analysis was used to control for history of depression, psychiatric co-morbidity, sociodemographics and interpractice variation.
Multilevel analysis showed that patients with pre-existing ischaemic heart disease (72.1%) or cardiac arrhythmia (59.3%) were significantly less likely to have any depression care being initiated by their GP than patients without chronic somatic morbidity (88.0%). No other specific condition had a significant influence on GP initiation of any care for depression. Among the patients being prescribed antidepressant treatment by their GP, none of the conditions was significantly associated with being prescribed continuous treatment for 180 days.
Our study indicates that patients with ischaemic heart disease or cardiac arrhythmia have a lower likelihood of GP initiation of any care for depression after being newly diagnosed with depression by their GP. This finding points to the importance of developing interventions aimed at supporting GPs in the adequate management of co-morbid depression in heart disease patients to reduce the negative effects of this co-morbidity.
在初级保健机构中,关于特定慢性躯体疾病与共病抑郁症护理之间的关系,现有信息有限。因此,本项基于全科医疗的前瞻性研究对这种关系进行了考察。
分析了991例由全科医生(GP)新诊断为抑郁症患者的发病率、处方及转诊的纵向数据。考察了13种特定慢性躯体疾病对任何抑郁症护理启动以及180天持续抗抑郁治疗处方的影响。采用多水平逻辑回归分析来控制抑郁症病史、精神共病、社会人口统计学及医疗实践间差异。
多水平分析显示,与无慢性躯体疾病的患者(88.0%)相比,患有缺血性心脏病(72.1%)或心律失常(59.3%)的患者由全科医生启动任何抑郁症护理的可能性显著降低。没有其他特定疾病对全科医生启动任何抑郁症护理有显著影响。在由全科医生开抗抑郁药治疗的患者中,没有一种疾病与接受180天持续治疗有显著关联。
我们的研究表明,患有缺血性心脏病或心律失常的患者在被全科医生新诊断为抑郁症后,全科医生启动任何抑郁症护理的可能性较低。这一发现指出了开展干预措施的重要性,旨在支持全科医生对心脏病患者共病抑郁症进行适当管理,以减少这种共病的负面影响。