Chen Kai-yun, Xiang Guo-an, Wang Han-ning, Gao Peng, Xiao Fang-lian
Department of Minimal Invasive Surgery Center, Second People's Hospital of Guangdong Province, Guangzhou 510317, China.
Zhonghua Wai Ke Za Zhi. 2007 Jun 1;45(11):750-2.
To study the effect of laparoscopy and digital subtraction angiography in the treatment of severe acute pancreatitis (SAP).
Seventy-five SAP patients were randomly divided into tow groups: (1) Conventional treatment group (group A, n = 35); (2) Conventional treatment combined with laparoscopy and digital subtraction angiography treatment group (group B, n = 40). The clinical parameters and treatment results in the 2 groups were compared.
After treatment, APACHE II score in group B was significantly lower than that in group A (P < 0.05). The functions of liver, renal and lung were recovered (P < 0.05, respectively), levels of serum TNF-alpha and IL-1 beta were significantly lower, but IL-10 significantly elevated (P < 0.05), the CT SPN was much lower (P < 0.05); rate of organ failure significantly decreased (P < 0.01), the successful rate of organ failure treatment was increased (P < 0.05); the in hospital mortality decreased (all P < 0.05).
Laparoscopy and digital subtraction angiography in combination with conventional treatment for SAP significantly improves the outcome and decrease the mortality of SAP.
