Russell M H, Murray I J, Metcalfe R A, Kulikowski J J
Department of Optometry and Vision Sciences, UMIST, Manchester, UK.
Brain. 1991 Dec;114 ( Pt 6):2419-35. doi: 10.1093/brain/114.6.2419.
Chromatic and achromatic visual function were investigated using psychophysical and evoked potential techniques in 32 patients with multiple sclerosis (MS) or optic neuritis. There was no evidence for either chromatic or achromatic vision being selectively damaged. There was, however, some evidence that demyelination of the optic nerve causes a visual defect in which the transmission of high temporal frequencies is imparied. In some patients either a red or blue deficit was evident, but overall there was no evidence of a wavelength specific colour vision defect in our patient group. Reduction of chromatic sensitivity as determined psychophysically had a statistically significant correlation with the amplitude and latency of the chromatic visual evoked potential.
采用心理物理学和诱发电位技术，对32例多发性硬化症（MS）或视神经炎患者的色觉和非色觉视觉功能进行了研究。没有证据表明色觉或非色觉视觉受到选择性损害。然而，有一些证据表明，视神经脱髓鞘会导致一种视觉缺陷，即高时间频率的传递受损。在一些患者中，红色或蓝色缺陷明显，但总体而言，我们的患者组中没有证据表明存在波长特异性色觉缺陷。通过心理物理学测定的色觉敏感度降低与色觉视觉诱发电位的振幅和潜伏期具有统计学显著相关性。
