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广泛硬膜外脓肿和长节段骨髓炎的成功治疗:一例报告并文献复习

Successful treatment of extended epidural abscess and long segment osteomyelitis: a case report and review of the literature.

作者信息

Chang Wei-Chieh, Tsou Hsi-Kai, Kao Ting-Hsien, Yang Meng-Yin, Shen Chiung-Chyi

机构信息

Department of Neurosurgery, Taichung Veterans General Hospital, Taichung, Taiwan 407, Republic of China.

出版信息

Surg Neurol. 2008 Feb;69(2):117-20; discussion 120. doi: 10.1016/j.surneu.2006.12.047. Epub 2007 Sep 6.

Abstract

BACKGROUND

Spinal osteomyelitis and epidural abscess are complicated medical conditions. Diagnosis is often delayed because of cormorbidity. The time of instrumentation is still controversial. However, there is no doubting the indication of spinal hardware implantation when spinal fusion is needed. Long segment osteomyelitis and extended epidural abscess are rare. The treatment is challenging for neurosurgeons. We report a case of extended epidural abscesses and long segments of osteomyelitis.

METHODS

One-stage meticulous debridement, anterior cervical corpectomies, and spinal fusion with mesh cage and titanium plate were performed on the patient. Hyperbaric oxygenation and 6 weeks of intravenous antibiotics were prescribed as adjuvant therapy.

RESULTS

Both clinical presentations and imaging studies showed a good response to the treatment. The patient returned to his life 3 months later.

CONCLUSIONS

This case illustrates that spinal instrumentation is not an absolute contraindication in the presence of epidural abscesses and vertebral osteomyelitis. Combined surgical debridement at a critical level, with adjuvant antibiotics and hyperbaric oxygenation, is a safe and effective therapy in those with neurologic deficits, spinal instability, and extended epidural abscess.

摘要

背景

脊柱骨髓炎和硬膜外脓肿是复杂的医学病症。由于合并症,诊断常常延迟。器械植入的时机仍存在争议。然而,当需要脊柱融合时,脊柱内固定植入的指征是毋庸置疑的。长节段骨髓炎和广泛的硬膜外脓肿较为罕见。对于神经外科医生而言,治疗颇具挑战性。我们报告一例广泛硬膜外脓肿和长节段骨髓炎的病例。

方法

对该患者进行一期细致清创、前路颈椎椎体次全切除,并采用椎间融合器和钛板进行脊柱融合。给予高压氧治疗及6周静脉抗生素作为辅助治疗。

结果

临床表现和影像学检查均显示对治疗反应良好。患者3个月后恢复正常生活。

结论

该病例表明,在存在硬膜外脓肿和椎体骨髓炎的情况下,脊柱内固定并非绝对禁忌。在关键节段进行联合手术清创,并辅以抗生素和高压氧治疗,对于有神经功能缺损、脊柱不稳定和广泛硬膜外脓肿的患者是一种安全有效的治疗方法。

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