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Electrical stimulation of dorsal, but not ventral hippocampus reduces behavioral defense in the elevated plus maze and shock-probe burying test in rats.

作者信息

Dringenberg Hans C, Levine Yonina, Menard Janet L

机构信息

Department of Psychology, Queen's University, Kingston, Ontario K7L 3N6, Canada.

出版信息

Behav Brain Res. 2008 Jan 10;186(1):143-7. doi: 10.1016/j.bbr.2007.07.030. Epub 2007 Jul 28.

DOI:10.1016/j.bbr.2007.07.030
PMID:17825440
Abstract

Recent evidence indicates that the hippocampus contributes to the control of defensive behaviors in rodents. Here, electrical stimulation (1s, 60 Hz) of the rat dorsal hippocampus inhibited defense in the elevated plus maze (increased open arm exploration) and shock-probe burying test (reduced burying duration), while ventral hippocampal stimulation had no effects. Thus, the dorsal hippocampus may play an important role in modulating a range of defensive strategies.

摘要

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