Sampedro Marta Fernandez, Patel Robin
Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.
Infect Dis Clin North Am. 2007 Sep;21(3):785-819, x. doi: 10.1016/j.idc.2007.07.001.
The extensive and ever-increasing use of long-term prosthetic devices has improved quality of life and survival for many patients. Prosthetic device-related infection occurs infrequently but is associated with significant morbidity and mortality. Management is challenging, often requiring prolonged antimicrobial therapy and surgical intervention. Better understanding of the interaction between microorganisms, devices, and the host should improve the ability to manage device-related infections. This article reviews recent advances in the diagnosis and treatment of infections associated with indwelling medical devices, highlighting those associated with prosthetic joints, cerebrospinal fluid shunts, and prosthetic heart valves.
长期使用的假体装置的广泛且不断增加的应用改善了许多患者的生活质量并延长了生存期。与假体装置相关的感染虽不常见，但却与显著的发病率和死亡率相关。其管理具有挑战性，常常需要长期的抗菌治疗和外科干预。更好地理解微生物、装置和宿主之间的相互作用应能提高处理与装置相关感染的能力。本文综述了与植入性医疗器械相关感染的诊断和治疗方面的最新进展，重点介绍了与人工关节、脑脊液分流管和人工心脏瓣膜相关的感染。
