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未确诊头晕的前庭诱发肌源性电位

Vestibular evoked myogenic potentials of undiagnosed dizziness.

作者信息

Seo Toru, Miyamoto Atsushi, Node Michiko, Sakagami Masafumi

机构信息

Department of Otolaryngology, Takarazuka Municipal Hospital, 4-5-1 Kohama, Takarazuka, Hyogo 665-0827, Japan.

出版信息

Auris Nasus Larynx. 2008 Mar;35(1):27-30. doi: 10.1016/j.anl.2007.04.006. Epub 2007 Sep 10.

DOI:10.1016/j.anl.2007.04.006
PMID:17826932
Abstract

OBJECTIVE

Recording of vestibular evoked myogenic potentials (VEMP) can facilitate the evaluation of otolith function. The dizziness caused by otolith lesions is not completely understood. To clarify which symptoms of dizziness originate from the otolith organs, we examined the relationship between symptoms and VEMP results in patients with undiagnosed dizziness.

METHODS

The subjects were 18 patients with undiagnosed dizziness aged less than 40 years who underwent VEMP examination. The VEMP results were evaluated using the interaural ratio of p13-n23 amplitude.

RESULTS

Abnormal VEMP results were obtained in five of seven patients who experienced a sensation of falling (p=0.013), in none of the three patients who experienced a swaying sensation (p>0.05), and in one of eight patients who experienced a floating sensation (p>0.05). Five of six patients with abnormal VEMP results complained of disequilibrium lasting a few seconds.

CONCLUSIONS

Dizziness with a sensation of falling lasting for a few seconds was related to abnormal VEMP results, suggesting that it resulted from saccular dysfunction. VEMP examination may be considered a useful modality in the diagnosis of dizziness of unknown origin.

摘要

目的

记录前庭诱发肌源性电位(VEMP)有助于评估耳石功能。耳石病变引起的头晕尚未完全明确。为了阐明哪些头晕症状源于耳石器官,我们研究了未确诊头晕患者的症状与VEMP结果之间的关系。

方法

研究对象为18例年龄小于40岁的未确诊头晕患者,均接受了VEMP检查。采用p13-n23波幅的双耳比值评估VEMP结果。

结果

7例有跌倒感的患者中有5例VEMP结果异常(p = 0.013),3例有摇摆感的患者中无一例VEMP结果异常(p>0.05),8例有漂浮感的患者中有1例VEMP结果异常(p>0.05)。VEMP结果异常的6例患者中有5例主诉持续数秒的平衡失调。

结论

持续数秒的跌倒感头晕与VEMP结果异常有关,提示其由球囊功能障碍引起。VEMP检查可被视为诊断不明原因头晕的一种有用方法。

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