Ramcharitar Steve, Ligthart Jurgen, Van der Giessen Willem J
Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
J Invasive Cardiol. 2007 Sep;19(9):E276-7.
We describe a case of very late stent thrombosis (LST) occurring 18 months after implantation of a Taxus stent in an insulin-dependent diabetic patient after stopping his antiplatelet therapy. Intravascular ultrasound performed during his acute admission showed gross undersizing of his stent that was originally sized with quantitative coronary angiography. It highlights the importance of the overreliance on a single quantitative technique and suggests that the abnormally induced shear stresses through the reduced vessel caliber, augmented by a distal lesion, can result in LST when clopidogrel is stopped.
我们描述了一例胰岛素依赖型糖尿病患者在停用抗血小板治疗18个月后，发生的紫杉醇支架极晚期血栓形成（LST）病例。急性入院期间进行的血管内超声显示，其支架严重尺寸过小，而该支架最初是通过定量冠状动脉造影来确定尺寸的。这突出了过度依赖单一量化技术的重要性，并表明当停用氯吡格雷时，因血管口径减小以及远端病变加剧而异常诱导的剪切应力可导致LST。
