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肝细胞癌的管理

Management of hepatocellular carcinoma.

作者信息

De Giorgio M, Fagiuoli S

机构信息

Dipartimento Medicina Specialistica e dei Trapianti, U.O. Gastroenterologia, Bergamo, Italy.

出版信息

Dig Dis. 2007;25(3):279-81. doi: 10.1159/000103902.

DOI:10.1159/000103902
PMID:17827957
Abstract

The aim of this review was to assess the correct clinical management of hepatocellular carcinoma (HCC). Following the diagnosis, the correct choice of treatment must take into account both the anatomical/biological features of HCC and the functional status of the underlying cirrhosis. As of today, only the application of the BCLC scoring system, which stratifies patients according to HCC staging and degree of liver disease in a process leading to a specific treatment, has shown the best results in terms of survival.

摘要

本综述的目的是评估肝细胞癌(HCC)的正确临床管理。诊断后,治疗的正确选择必须同时考虑HCC的解剖学/生物学特征以及潜在肝硬化的功能状态。截至目前,只有应用BCLC评分系统,根据HCC分期和肝病程度对患者进行分层,进而得出特定的治疗方案,在生存率方面显示出了最佳效果。

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Management of hepatocellular carcinoma.肝细胞癌的管理
Dig Dis. 2007;25(3):279-81. doi: 10.1159/000103902.
2
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Spontaneous rupture of hepatocellular carcinoma: a review of 172 Japanese cases.肝细胞癌自发性破裂:172例日本病例回顾
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Comparison of seven staging systems in cirrhotic patients with hepatocellular carcinoma in a cohort of patients who underwent radiofrequency ablation with complete response.在一组接受射频消融且完全缓解的肝硬化肝细胞癌患者中,对七种分期系统的比较。
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[Hepatocellular carcinoma: a multidisciplinary approach].[肝细胞癌:多学科治疗方法]
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[Classifications and prognosis of hepatocellular carcinoma].[肝细胞癌的分类与预后]
Khirurgiia (Sofiia). 2002;58(1):11-4.
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Modern diagnosis and management of hepatocellular carcinoma.肝细胞癌的现代诊断与管理
Clin Liver Dis. 2009 May;13(2):233-47. doi: 10.1016/j.cld.2009.02.007.
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[Hepatocellular carcinoma screening in patients with cirrhosis: a large French multicentric study (HCC)].肝硬化患者的肝细胞癌筛查:一项大型法国多中心研究(HCC)
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Hepatocellular carcinoma associated with hereditary hemochromatosis occurring in non-cirrhotic liver.遗传性血色素沉着症相关的肝细胞癌发生于非肝硬化肝脏。
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Hepatocellular carcinoma development in cirrhosis.肝硬化中肝细胞癌的发生
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长链非编码RNA GAS6-AS2通过激活PI3K/AKT/FoxO3a信号通路促进肝细胞癌的肿瘤生长和转移。
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DEPDC1 promotes cell proliferation and suppresses sensitivity to chemotherapy in human hepatocellular carcinoma.DEP 结构域蛋白 1 促进人肝癌细胞增殖并抑制其对化疗的敏感性。
Biosci Rep. 2019 Jul 10;39(7). doi: 10.1042/BSR20190946. Print 2019 Jul 31.
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Sulfasalazine attenuates evading anticancer response of CD133-positive hepatocellular carcinoma cells.柳氮磺胺吡啶减弱CD133阳性肝癌细胞的逃避抗癌反应。
J Exp Clin Cancer Res. 2017 Mar 3;36(1):38. doi: 10.1186/s13046-017-0511-7.
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Overexpression of Aristaless-Like Homeobox-4 Inhibits Proliferation, Invasion, and EMT in Hepatocellular Carcinoma Cells.无翅型MMTV整合位点家族成员4同源盒基因4的过表达抑制肝癌细胞的增殖、侵袭和上皮-间质转化
Oncol Res. 2017 Jan 2;25(1):11-18. doi: 10.3727/096504016X14685034103833.
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Hepatic stellate cells secreted hepatocyte growth factor contributes to the chemoresistance of hepatocellular carcinoma.肝星状细胞分泌的肝细胞生长因子有助于肝癌的化疗耐药。
PLoS One. 2013 Sep 2;8(9):e73312. doi: 10.1371/journal.pone.0073312. eCollection 2013.
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The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma.多免疫球蛋白受体在炎症诱导的人肝癌肿瘤转移中的作用。
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Tumor initiation and progression in hepatocellular carcinoma: risk factors, classification, and therapeutic targets.肝细胞癌的肿瘤发生和进展:危险因素、分类和治疗靶点。
Acta Pharmacol Sin. 2010 Nov;31(11):1409-20. doi: 10.1038/aps.2010.142. Epub 2010 Oct 18.
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MRI versus 64-row MDCT for diagnosis of hepatocellular carcinoma.磁共振成像与 64 排多层螺旋 CT 诊断肝细胞癌的对比研究。
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