Kristiansen Hans Morten, Faerestrand Svein
Hjerteavdelingen, Haukeland Universitetssjukehus, 5021 Bergen.
Tidsskr Nor Laegeforen. 2007 Sep 6;127(17):2226-9.
Cardiac resynchronization therapy (CRT) is an established method for treatment of patients with severe congestive heart failure and asynchronous left ventricular contraction. Its clinical and haemodynamic benefits are well documented. We have retrospectively reviewed CRT performed at our centre.
Our department treated 150 patients with CRT according to accepted indications from 1999-2006. The patients were observed for two years and one third reached two-year follow-up. We reviewed operative complications, lead re-implantations, clinical benefits, pacing thresholds, electrogram amplitudes and lead impedance..
There were 20% lead re-implantations after two years of follow-up and a significant improvement in NYHA functional capacity. For the coronary venous lead the average stimulation threshold was stable at 1.2-1.3 V at 0.5 ms, the sensing electrogram amplitude was 10-18 mV and the impedance was 600 ohm at 5.0 V during follow-up. Similar stable electrophysiological values were measured for the right ventricular lead and the atrial lead.
There were in general few peroperative complications. All implanted leads in CRT showed stable- and low threshold values during a two-year follow-up period.
心脏再同步治疗(CRT)是治疗重度充血性心力衰竭和左心室收缩不同步患者的既定方法。其临床和血流动力学益处已得到充分证明。我们对在本中心进行的CRT治疗进行了回顾性研究。
1999年至2006年,我们科室根据公认的适应症对150例患者进行了CRT治疗。对患者进行了两年观察,三分之一的患者进行了两年随访。我们回顾了手术并发症、导线重新植入、临床益处、起搏阈值、心电图振幅和导线阻抗。
随访两年后,20%的患者进行了导线重新植入,纽约心脏协会(NYHA)心功能分级有显著改善。对于冠状静脉导线,随访期间平均刺激阈值在0.5毫秒时稳定在1.2 - 1.3伏,感知心电图振幅为10 - 18毫伏,在5.0伏时阻抗为600欧姆。右心室导线和心房导线也测得类似的稳定电生理值。
一般手术并发症较少。CRT中所有植入导线在两年随访期内均显示出稳定且低的阈值。